atlas translation standard v14 trial download

Oxygen therapy is an essential medication that is poorly available to sick children globally, despite clear evidence of benefit and wide clinical application. Retrospectively registered on 6 March 2017. Trial registrationĪustralian New Zealand Clinical Trials Registry: ACTRN12617000341325. Our results should have important implications for policy-makers, hospital administrators, and child health organisations in Africa and globally. Our study will provide quality evidence on the effectiveness of improved oxygen systems, and how to better implement and scale-up oxygen systems in resource-limited settings. The planned study duration is from 2015 to 2018. Secondary outcome measures include a range of clinical, quality of care, technical, and health systems outcomes.

Our primary outcome measures are childhood pneumonia case fatality rate and inpatient neonatal mortality rate. Our mixed-methods evaluation will evaluate effectiveness, impact, sustainability, process and fidelity. We are using a stepped-wedge cluster randomised design with participating hospitals randomised to receive an improved oxygen system at 4-month steps (three hospitals per step). We have based the intervention design on a theory-based analysis of previous oxygen projects, and used quality improvement principles, evidence-based teaching methods, and behaviour-change strategies. Phase 1 will involve the introduction of pulse oximetry alone phase 2 will involve the introduction of the full, improved oxygen system package. The improved oxygen system includes: a standardised equipment package training of clinical and technical staff infrastructure support (including improved power supply) and quality improvement activities such as supportive supervision.

This trial will evaluate the implementation of improved oxygen systems at secondary-level hospitals in southwest Nigeria. However, providing oxygen to children is challenging, especially in small hospitals with weak infrastructure and low human resource capacity. Improved oxygen systems can reduce childhood pneumonia mortality substantially. Oxygen is a life-saving, essential medicine that is important for the treatment of many common childhood conditions.

Atlas translation standard v14 trial download